Immunofluorescence staining of A549 cells with CSB-PA011764LA01HU at 1:33, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

INTS6 Antibody

CSB-PA011764LA01HU

ApplicationsImmunoFluorescence, ELISA

Product group Antibodies

ReactivityHuman

TargetINTS6

Overview

Supplier
Cusabio
Product Name
INTS6 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, ELISA
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID26512
Target name
INTS6
Target description
integrator complex subunit 6
Target synonyms
DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2, integrator complex subunit 6, DEAD box protein, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26, RNA helicase HDB, protein deleted in cancer 1
Host
Rabbit
Isotype
IgG
Protein IDQ9UL03
Protein Name
Integrator complex subunit 6
Scientific Description
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267). May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth (PubMed:15254679, PubMed:16239144).
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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INTS6 Antibody

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