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InVivoMAb anti-human CD1a
BE0211
ApplicationsFlow Cytometry, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
Overview
- SupplierBio X Cell
- Product NameInVivoMAb anti-human CD1a
- Delivery Days Customer7
- ApplicationsFlow Cytometry, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDOKT-6
- Concentration4-11 mg/ml
- Estimated Purity>95%
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe OKT-6 monoclonal antibody reacts with human CD1a a member of the CD1 family of transmembrane glycoproteins. The CD1 proteins are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with β2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Elevated and cross-responsive CD1a-reactive T cells in bee and wasp venom allergic individuals. Subramaniam S et al., 2016 Jan, Eur J ImmunolRead more
- Bee venom processes human skin lipids for presentation by CD1a. Bourgeois EA et al., 2015 Feb 9, J Exp MedRead more
- CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens. de Jong A et al., 2014 Feb, Nat ImmunolRead more
- Human CD1a deficiency is common and genetically regulated. Seshadri C et al., 2013 Aug 15, J ImmunolRead more
- CD1c tetramers detect ex vivo T cell responses to processed phosphomycoketide antigens. Ly D et al., 2013 Apr 8, J Exp MedRead more
- Lipoproteins are major targets of the polyclonal human T cell response to Mycobacterium tuberculosis. Seshadri C et al., 2013 Jan 1, J ImmunolRead more
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Product group Antibodies
References
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