InVivoMAb anti-human CD3

OKT3 prevents xenogeneic GVHD and allows reliable xenograft initiation from unfractionated human hematopoietic tissues. Wunderlich M et al., 2014 Jun 12, Blood

Pharmacology of anti-CD3 diphtheria immunotoxin in CD3 positive T-cell lymphoma trials. Woo JH et al., 2010, Methods Mol Biol

Differential antibody binding to the surface alphabetaTCR.CD3 complex of CD4+ and CD8+ T lymphocytes is conserved in mammals and associated with differential glycosylation. Rossi NE et al., 2008 Oct, Int Immunol

Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment. Arnett KL et al., 2004 Nov 16, Proc Natl Acad Sci U S A