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InVivoMAb anti-human GM-CSF
BE0384
Overview
- SupplierBio X Cell
- Product NameInVivoMAb anti-human GM-CSF
- Delivery Days Customer7
- ApplicationsELISA, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDBVD2-23B6
- Concentration4-11 mg/ml
- Estimated Purity>95%
- HostRat
- IsotypeIgG2a
- Scientific DescriptionThe BVD2-23B6 monoclonal antibody reacts with human granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2). GM-CSF is a 14 kDa monomeric hematopoietic factor secreted by macrophages, T cells, mast cells, NK cells, endothelial cells, and fibroblasts. GM-CSF stimulates stem cells to differentiate into granulocytes (neutrophils, eosinophils, and basophils) and monocytes. The BVD2-23B6 antibody has been reported as a neutralizing antibody.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer. Takeuchi S et al., 2015 Jul 1, Cancer ResRead more
- GM-CSF production by glioblastoma cells has a functional role in eosinophil survival, activation, and growth factor production for enhanced tumor cell proliferation. Curran CS et al., 2011 Aug 1, J ImmunolRead more
- Proliferative and synthetic airway smooth muscle cells are overlapping populations. Sukkar MB et al., 2004 Oct, Immunol Cell BiolRead more
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Product group Antibodies
References
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