InVivoMAb anti-human mesothelin

Nicolaides NC, Kline JB, Grasso L. NAV-001, a high-efficacy antibody-drug conjugate targeting mesothelin with improved delivery of a potent payload by counteracting MUC16/CA125 inhibitory effects. PLoS One. 2023,18(5):e0285161. doi: 10.1371/journal.pone.0285161

Tomar S, Zhang J, Khanal M, et al. Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors. Mol Cancer Ther. 2022,21(7):1195-1206. doi: 10.1158/1535-7163.MCT-22-0073

Zhang Z, Jiang D, Yang H, et al. Modified CAR T cells targeting membrane-proximal epitope of mesothelin enhances the antitumor function against large solid tumor. Cell Death Dis. 2019,10(7):476. doi: 10.1038/s41419-019-1711-1

Zhang YF, Ho M. Humanization of rabbit monoclonal antibodies via grafting combined Kabat/IMGT/Paratome complementarity-determining regions: Rationale and examples. MAbs. 2017,9(3):419-429. doi: 10.1080/19420862.2017.1289302

Nagaya T, Nakamura Y, Sato K, et al. Near infrared photoimmunotherapy with an anti-mesothelin antibody. Oncotarget. 2016,7(17):23361-9. doi: 10.18632/oncotarget.8025

Zhang YF, Phung Y, Gao W, et al. New high affinity monoclonal antibodies recognize non-overlapping epitopes on mesothelin for monitoring and treating mesothelioma. Sci Rep. 2015,5:9928. doi: 10.1038/srep09928