Product image
Product image
InVivoMAb anti-human YB-1
BE0216
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
Overview
- SupplierBio X Cell
- Product NameInVivoMAb anti-human YB-1
- Delivery Days Customer7
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID21A3
- Concentration4-11 mg/ml
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe 21A3 monoclonal antibody reacts with human Y-box binding protein 1 (YB-1) a highly conserved protein that has broad nucleic acid binding properties. YB-1 binds DNA and RNA and plays a role in multiple cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. YB-1 is also a component of messenger ribonucleoprotein complexes and may have a role in microRNA processing. Aberrant expression of YB-1 is associated with cancer proliferation in numerous tissues.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Y-box binding protein-1 expression in diffuse large B-cell lymphoma: an impact on prognosis in the rituximab era. Hanzawa K et al., 2010 Nov, Leuk LymphomaRead more
- The up-regulation of Y-box binding proteins (DNA binding protein A and Y-box binding protein-1) as prognostic markers of hepatocellular carcinoma. Yasen M et al., 2005 Oct 15, Clin Cancer ResRead more
