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InVivoMAb anti-human/rat HER2 (neu)

Research Use Only
BE0277
Bio X Cell
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Other Application
Product group Antibodies
ReactivityHuman, Rat
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Overview

  • Supplier
    Bio X Cell
  • Product Name
    InVivoMAb anti-human/rat HER2 (neu)
  • Delivery Days Customer
    7
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    7.16.4
  • Concentration
    4-11 mg/ml
  • Estimated Purity
    >95%
  • Host
    Mouse
  • Isotype
    IgG2a
  • Reactivity
    Human, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Sequential Anti-PD1 Therapy Following Dendritic Cell Vaccination Improves Survival in a HER2 Mammary Carcinoma Model and Identifies a Critical Role for CD4 T Cells in Mediating the Response. Kodumudi KN et al., 2019, Front Immunol
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  • Single-cell profiling guided combinatorial immunotherapy for fast-evolving CDK4/6 inhibitor-resistant HER2-positive breast cancer. Wang Q et al., 2019 Aug 23, Nat Commun
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  • The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity. Park S et al., 2010 Aug 9, Cancer Cell
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  • Neu antigen-negative variants can be generated after neu-specific antibody therapy in neu transgenic mice. Knutson KL et al., 2004 Feb 1, Cancer Res
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  • Shared antigenic epitopes and pathobiological functions of anti-p185(her2/neu) monoclonal antibodies. Zhang H et al., 1999 Sep, Exp Mol Pathol
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  • Monoclonal antibodies identify a cell-surface antigen associated with an activated cellular oncogene. Drebin JA et al., 1984 Dec 6-12, Nature
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  • Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen. Drebin JA et al., 1986 Dec, Proc Natl Acad Sci U S A
    Read more

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