InVivoMAb anti-LCMV nucleoprotein

Name: InVivoMAb anti-LCMV nucleoprotein
SKU: BE0106_B56
Availability: BackOrder

BE0106

ApplicationsFlow Cytometry, ImmunoFluorescence

Product group Antibodies

ReactivityVirus

Overview

Supplier
Bio X Cell
Product Name
InVivoMAb anti-LCMV nucleoprotein
Delivery Days Customer
7
Applications
Flow Cytometry, ImmunoFluorescence
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
VL-4
Concentration
4-11 mg/ml
Estimated Purity
>95%
Host
Rat
Isotype
IgG2a
Scientific Description
The VL-4 antibody reacts with lymphocytic choriomeningitis virus (LCMV) nucleoprotein (NP), a 63 kDa structural protein. This antibody was generated by fusion of spleen cells of an LCMV strain WE immunized F1 rat with the YM3 myeloma cell line. This antibody has been shown to stain LCMV-infected cell internally with no surface staining. This antibody does not react with vaccinia, vesicular stomatitis or influenza virus-infected cells in the case of internal or surface staining.
Reactivity
Virus
Storage Instruction
2°C to 8°C
UNSPSC
12352203

Therapeutic antiviral T cells noncytopathically clear persistently infected microglia after conversion into antigen-presenting cells. Herz J et al., 2015 Jul 27, J Exp Med
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Blockade of interferon Beta, but not interferon alpha, signaling controls persistent viral infection. Ng CT et al., 2015 May 13, Cell Host Microbe
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A ceramide analogue stimulates dendritic cells to promote T cell responses upon virus infections. Pritzl CJ et al., 2015 May 1, J Immunol
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Early virus-host interactions dictate the course of a persistent infection. Sullivan BM et al., 2015 Jan, PLoS Pathog
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Lymphocytic choriomeningitis virus persistence promotes effector-like memory differentiation and enhances mucosal T cell distribution. Beura LK et al., 2015 Feb, J Leukoc Biol
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Sphingosine analog AAL-R promotes activation of LCMV-infected dendritic cells. Seo YJ et al., 2014 Mar, Viral Immunol
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Type I interferon programs innate myeloid dynamics and gene expression in the virally infected nervous system. Nayak D et al., 2013, PLoS Pathog
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