InVivoMAb anti-mouse CD172a (SIRPalpha)

Anti-SIRPalpha antibodies as a potential new tool for cancer immunotherapy. Yanagita T et al., 2017 Jan 12, JCI Insight

Inflammation-induced proteolytic processing of the SIRPalpha cytoplasmic ITIM in neutrophils propagates a proinflammatory state. Zen K et al., 2013, Nat Commun

Lack of CD47 impairs bone cell differentiation and results in an osteopenic phenotype in vivo due to impaired signal regulatory protein alpha (SIRPalpha) signaling. Koskinen C et al., 2013 Oct 11, J Biol Chem

Expression of recipient CD47 on rat insulinoma cell xenografts prevents macrophage-mediated rejection through SIRPalpha inhibitory signaling in mice. Teraoka Y et al., 2013, PLoS One

Osteoclast formation is strongly reduced both in vivo and in vitro in the absence of CD47/SIRPalpha-interaction. Lundberg P et al., 2007 Jan 12, Biochem Biophys Res Commun

CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complement receptor-mediated phagocytosis. Oldenborg PA et al., 2001 Apr 2, J Exp Med