InVivoMAb anti-mouse CD172a (SIRPalpha)
BE0322
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, Neutralisation/Blocking
Product group Antibodies
ReactivityMouse
Overview
- SupplierBio X Cell
- Product NameInVivoMAb anti-mouse CD172a (SIRPalpha)
- Delivery Days Customer7
- ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDP84
- Concentration4-11 mg/ml
- Estimated Purity>95%
- HostRat
- IsotypeIgG1
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Yanagita T, Murata Y, Tanaka D, et al. Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy. JCI Insight. 2017,2(1):e89140. doi: 10.1172/jci.insight.89140Read this paper
- Zen K, Guo Y, Bian Z, et al. Inflammation-induced proteolytic processing of the SIRPα cytoplasmic ITIM in neutrophils propagates a proinflammatory state. Nat Commun. 2013,4:2436. doi: 10.1038/ncomms3436Read this paper
- Koskinen C, Persson E, Baldock P, et al. Lack of CD47 impairs bone cell differentiation and results in an osteopenic phenotype in vivo due to impaired signal regulatory protein α (SIRPα) signaling. J Biol Chem. 2013,288(41):29333-44. doi: 10.1074/jbc.M113.494591Read this paper
- Teraoka Y, Ide K, Morimoto H, et al. Expression of recipient CD47 on rat insulinoma cell xenografts prevents macrophage-mediated rejection through SIRPα inhibitory signaling in mice. PLoS One. 2013,8(3):e58359. doi: 10.1371/journal.pone.0058359Read this paper
- Lundberg P, Koskinen C, Baldock PA, et al. Osteoclast formation is strongly reduced both in vivo and in vitro in the absence of CD47/SIRPalpha-interaction. Biochem Biophys Res Commun. 2007,352(2):444-8.Read this paper
- Oldenborg PA, Gresham HD, Lindberg FP. CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complement receptor-mediated phagocytosis. J Exp Med. 2001,193(7):855-62.Read this paper
