InVivoMAb anti-mouse CSF1

CD47 blockade triggers T cell-mediated destruction of immunogenic tumors. Liu X et al., 2015 Oct, Nat Med

DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance. Conde P et al., 2015 Jun 16, Immunity

Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells. Ruffell B et al., 2014 Nov 10, Cancer Cell

CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models. Zhu Y et al., 2014 Sep 15, Cancer Res

JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia. Manthey CL et al., 2009 Nov, Mol Cancer Ther