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InVivoMAb anti-mouse CXCL10 (IP-10)

BE0440
Bio X Cell
ApplicationsFunctional Assay, Western Blot, ELISA, Neutralisation/Blocking
Product group Antibodies
ReactivityMouse
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Overview

  • Supplier
    Bio X Cell
  • Product Name
    InVivoMAb anti-mouse CXCL10 (IP-10)
  • Delivery Days Customer
    7
  • Applications
    Functional Assay, Western Blot, ELISA, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1F11
  • Concentration
    4-11 mg/ml
  • Estimated Purity
    >95%
  • Host
    Hamster
  • Isotype
    IgG
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Pöysti S, Silojärvi S, Brodnicki TC, et al. Gut dysbiosis promotes islet-autoimmunity by increasing T-cell attraction in islets via CXCL10 chemokine. J Autoimmun. 2023,140:103090. doi: 10.1016/j.jaut.2023.103090
    Read this paper
  • Gaylo-Moynihan A, Prizant H, Popović M, et al. Programming of Distinct Chemokine-Dependent and -Independent Search Strategies for Th1 and Th2 Cells Optimizes Function at Inflamed Sites. Immunity. 2019,51(2):298-309.e6. doi: 10.1016/j.immuni.2019.06.026
    Read this paper
  • Chow MT, Ozga AJ, Servis RL, et al. Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy. Immunity. 2019,50(6):1498-1512.e5. doi: 10.1016/j.immuni.2019.04.010
    Read this paper
  • Tajfirouz D, West DM, Yin XT, et al. CXCL9 compensates for the absence of CXCL10 during recurrent Herpetic stromal keratitis. Virology. 2017,506:7-13. doi: 10.1016/j.virol.2017.02.022
    Read this paper
  • Bonvin P, Gueneau F, Buatois V, et al. Antibody Neutralization of CXCL10 in Vivo Is Dependent on Binding to Free and Not Endothelial-bound Chemokine: IMPLICATIONS FOR THE DESIGN OF A NEW GENERATION OF ANTI-CHEMOKINE THERAPEUTIC ANTIBODIES. J Biol Chem. 2017,292(10):4185-4197. doi: 10.1074/jbc.M116.745877
    Read this paper
  • Bender C, Christen S, Scholich K, et al. Islet-Expressed CXCL10 Promotes Autoimmune Destruction of Islet Isografts in Mice With Type 1 Diabetes. Diabetes. 2017,66(1):113-126. doi: 10.2337/db16-0547
    Read this paper
  • Homann D. Back From the Brink: The Uses of Targeting the CXCL10:CXCR3 Axis in Type 1 Diabetes. Diabetes. 2015,64(12):3990-2. doi: 10.2337/dbi15-0019
    Read this paper
  • Lasch S, Müller P, Bayer M, et al. Anti-CD3/Anti-CXCL10 Antibody Combination Therapy Induces a Persistent Remission of Type 1 Diabetes in Two Mouse Models. Diabetes. 2015,64(12):4198-211. doi: 10.2337/db15-0479
    Read this paper
  • Rashighi M, Agarwal P, Richmond JM, et al. CXCL10 is critical for the progression and maintenance of depigmentation in a mouse model of vitiligo. Sci Transl Med. 2014,6(223):223ra23. doi: 10.1126/scitranslmed.3007811
    Read this paper
  • Harris TH, Banigan EJ, Christian DA, et al. Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells. Nature. 2012,486(7404):545-8. doi: 10.1038/nature11098
    Read this paper