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InVivoMAb anti-mouse IL-18
BE0237
Overview
- SupplierBio X Cell
- Product NameInVivoMAb anti-mouse IL-18
- Delivery Days Customer7
- ApplicationsNeutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDYIGIF74-1G7
- Concentration4-11 mg/ml
- HostRat
- IsotypeIgG2a
- Scientific DescriptionThe YIGIF74-1G7 monoclonal antibody reacts with mouse IL-18, an 18 kDa pro-inflammatory cytokine. IL-18 is expressed by activated macrophages, keratinocytes, Kupffer cells, intestinal epithelial cells, and osteoblasts. IL-18 has been shown to activate NF-κB, induce Fas ligand expression, induce both CC and CXC chemokine expression, and enhance the production of IFNγ and GM-CSF.
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- The inflammasome potentiates influenza/Staphylococcus aureus superinfection in mice. Robinson KM et al., 2018 Apr 5, JCI InsightRead more
- S. aureus Evades Macrophage Killing through NLRP3-Dependent Effects on Mitochondrial Trafficking. Cohen TS et al., 2018 Feb 27, Cell RepRead more
- IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity. Molgora M et al., 2017 Nov 2, NatureRead more
- Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome. Chudnovskiy A et al., 2016 Oct 6, CellRead more
