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InVivoMAb anti-mouse Jagged 2

Research Use Only
BE0125
Bio X Cell
ApplicationsNeutralisation/Blocking
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Product group Antibodies
ReactivityMouse
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Overview

  • Supplier
    Bio X Cell
  • Product Name
    InVivoMAb anti-mouse Jagged 2
  • Delivery Days Customer
    7
  • Applications
    Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HMJ2-1
  • Concentration
    4-11 mg/ml
  • Estimated Purity
    >95%
  • Host
    Hamster
  • Isotype
    IgG
  • Scientific Description
    The HMJ2-1 monoclonal antibody reacts with mouse Jagged 2 one of many Notch ligands. Jagged 2 is expressed by thymic lymphoid and stromal cells, as well as macrophages and dendritic cells in the spleen. The Notch pathway is an important intercellular signaling pathway that plays a major role in controlling cell fate. The HMJ2-1 antibody has been shown to neutralize Jagged 2 in vivo.
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Jagged2-signaling promotes IL-6-dependent transplant rejection. Riella LV et al., 2013 Jun, Eur J Immunol
    Read more
  • Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells. Elyaman W et al., 2012 Apr 20, Immunity
    Read more

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