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InVivoMAb anti-mouse NKG2A/C/E

BE0321
Bio X Cell
ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
Product group Antibodies
ReactivityMouse
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Overview

  • Supplier
    Bio X Cell
  • Product Name
    InVivoMAb anti-mouse NKG2A/C/E
  • Delivery Days Customer
    7
  • Applications
    Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    20D5
  • Concentration
    4-11 mg/ml
  • Estimated Purity
    >95%
  • Host
    Rat
  • Isotype
    IgG2a
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • André P, Denis C, Soulas C, et al. Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells. Cell. 2018,175(7):1731-1743.e13. doi: 10.1016/j.cell.2018.10.014
    Read this paper
  • van Montfoort N, Borst L, Korrer MJ, et al. NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines. Cell. 2018,175(7):1744-1755.e15. doi: 10.1016/j.cell.2018.10.028
    Read this paper
  • Yang RK, Kalogriopoulos NA, Rakhmilevich AL, et al. Intratumoral hu14.18-IL-2 (IC) induces local and systemic antitumor effects that involve both activated T and NK cells as well as enhanced IC retention. J Immunol. 2012,189(5):2656-64. doi: 10.4049/jimmunol.1200934
    Read this paper
  • Vance RE, Jamieson AM, Raulet DH. Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells. J Exp Med. 1999,190(12):1801-12.
    Read this paper