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InVivoMAb anti-mouse TCR Vgamma1.1/Cr4
BE0257
ApplicationsFlow Cytometry, Other Application
Product group Antibodies
ReactivityMouse
Overview
- SupplierBio X Cell
- Product NameInVivoMAb anti-mouse TCR Vgamma1.1/Cr4
- Delivery Days Customer7
- ApplicationsFlow Cytometry, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2.11
- Concentration4-11 mg/ml
- Estimated Purity>95%
- HostHamster
- IsotypeIgG
- Scientific DescriptionThe 2.11 monoclonal antibody reacts with an epitope in the Cr4 domain of TCR Vγ1.1 (T cell receptor V gamma 1.1). The TCR is expressed on the surface of T lymphocytes and is responsible for recognizing fragments of antigen as peptides bound to MHC molecules. When the TCR engages with antigenic peptide and MHC the T lymphocyte is activated through signal transduction. The Vγ1Jγ4Cγ4 chain is expressed by a major population of γδ T cells in the thymus and peripheral lymphoid organs of adult mice. However, during postnatal and early life stages only a minor population of γδ T cells express Vγ1Jγ4Cγ4 during fetal and early postnatal life.
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Recruitment of Neutrophils Mediated by Vgamma2 gammadelta T Cells Deteriorates Liver Fibrosis Induced by Schistosoma japonicum Infection in C57BL/6 Mice. Zheng L et al., 2017 Aug, Infect ImmunRead more
- Intrathymic programming of effector fates in three molecularly distinct gammadelta T cell subtypes. Narayan K et al., 2012 Apr 1, Nat ImmunolRead more
