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InVivoMAb anti-mouse VEGF-A
BE0399
ApplicationsWestern Blot, Neutralisation/Blocking
Product group Antibodies
ReactivityMouse
Overview
- SupplierBio X Cell
- Product NameInVivoMAb anti-mouse VEGF-A
- Delivery Days Customer7
- ApplicationsWestern Blot, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2G11-2A05
- Concentration4-11 mg/ml
- Estimated Purity>95%
- HostRat
- IsotypeIgG2a
- Scientific DescriptionThe 2G11-2A05 monoclonal antibody reacts with mouse VEGF-A (vascular endothelial growth factor A). VEGF-A is a 45 kDa homodimeric, disulfide-linked glycoprotein that plays key roles in angiogenesis, vasculogenesis, and endothelial cell growth. It promotes mitogenesis, chemotaxis, and vascular permeability. Most tumors have a requirement for angiogenesis, and inhibition of VEGF binding to VEGF receptors has been the focus of several tumor therapeutic strategies. The 2G11-2A05 antibody neutralizes the biological activity of VEGF-A.
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway. Kumar V et al., 2010 Jun 10, BloodRead more