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InVivoMAb anti-mouse VEGFR-2
BE0060
ApplicationsWestern Blot, Neutralisation/Blocking
Product group Antibodies
ReactivityMouse
Overview
- SupplierBio X Cell
- Product NameInVivoMAb anti-mouse VEGFR-2
- Delivery Days Customer7
- ApplicationsWestern Blot, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDDC101
- Concentration4-11 mg/ml
- HostRat
- IsotypeIgG1
- Scientific DescriptionThe DC101 monoclonal antibody reacts with mouse VEGFR-2 (vascular endothelial growth factor receptor 2) also known as CD309, KDR, and Flk-1. VEGFR-2 is a member of the tyrosine protein kinase family. Upon binding to its ligand VEGF, VEGFR-2 pays key roles in vascular development and permeability. VEGFR-2 is expressed on endothelial cells at high levels in adult heart, lung, kidney, brain, and skeletal muscle as well as other tissues at lower levels. The DC101 antibody has been shown to inhibit VEGFR-2 signaling in vivo.
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- VEGF-Mediated Induction of PRD1-BF1/Blimp1 Expression Sensitizes Tumor Vasculature to Oncolytic Virus Infection. Arulanandam R et al., 2015 Aug 10, Cancer CellRead more
- Inhibition of vascular endothelial growth factor A and hypoxia-inducible factor 1alpha maximizes the effects of radiation in sarcoma mouse models through destruction of tumor vasculature. Lee HJ et al., 2015 Mar 1, Int J Radiat Oncol Biol PhysRead more
- Distinct functions of epidermal and myeloid-derived VEGF-A in skin tumorigenesis mediated by HPV8. Ding X et al., 2015 Jan 15, Cancer ResRead more
- Schlemms canal is a unique vessel with a combination of blood vascular and lymphatic phenotypes that forms by a novel developmental process. Kizhatil K et al., 2014 Jul, PLoS BiolRead more
- Contrasting responses of non-small cell lung cancer to antiangiogenic therapies depend on histological subtype. Larrayoz M et al., 2014 Apr, EMBO Mol MedRead more
- Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function. Villalta SA et al., 2013 Aug, DiabetesRead more
- Junctional adhesion molecule-A regulates vascular endothelial growth factor receptor-2 signaling-dependent mouse corneal wound healing. Chatterjee S et al., 2013, PLoS OneRead more
- Overcoming evasive resistance from vascular endothelial growth factor a inhibition in sarcomas by genetic or pharmacologic targeting of hypoxia-inducible factor 1alpha. Kim YJ et al., 2013 Jan 1, Int J CancerRead more
- Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway. Kumar V et al., 2010 Jun 10, BloodRead more
- Biomechanical regulation of blood vessel growth during tissue vascularization. Kilarski WW et al., 2009 Jun, Nat MedRead more
Related products
Product group Antibodies
References
ApplicationsWestern Blot, Neutralisation/Blocking
ReactivityMouse
- SizePrice
