InVivoMAb anti-West Nile virus NS1

Levels of Circulating NS1 Impact West Nile Virus Spread to the Brain.

Non-structural protein-1 is required for West Nile virus replication complex formation and viral RNA synthesis.

Evidence for a genetic and physical interaction between nonstructural proteins NS1 and NS4B that modulates replication of West Nile virus.

A short N-terminal peptide motif on flavivirus nonstructural protein NS1 modulates cellular targeting and immune recognition.

Antagonism of the complement component C4 by flavivirus nonstructural protein NS1.

Defining the levels of secreted non-structural protein NS1 after West Nile virus infection in cell culture and mice.

Antibody recognition of cell surface-associated NS1 triggers Fc-gamma receptor-mediated phagocytosis and clearance of West Nile Virus-infected cells.

Antibodies against West Nile Virus nonstructural protein NS1 prevent lethal infection through Fc gamma receptor-dependent and -independent mechanisms.