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InVivoMAb anti-WNV E protein DI-DII

BE0430
Bio X Cell
ApplicationsFlow Cytometry, ELISA, Neutralisation/Blocking, Other Application
Product group Antibodies
ReactivityVirus
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Overview

  • Supplier
    Bio X Cell
  • Product Name
    InVivoMAb anti-WNV E protein DI-DII
  • Delivery Days Customer
    7
  • Applications
    Flow Cytometry, ELISA, Neutralisation/Blocking, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    E53
  • Concentration
    4-11 mg/ml
  • Estimated Purity
    >95%
  • Host
    Mouse
  • Isotype
    IgG2a
  • Reactivity
    Virus
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Goo L, Debbink K, Kose N, et al. A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions. Nat Microbiol. 2019,4(1):71-77. doi: 10.1038/s41564-018-0283-7
    Read this paper
  • Goo L, VanBlargan LA, Dowd KA, et al. A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis. PLoS Pathog. 2017,13(2):e1006178. doi: 10.1371/journal.ppat.1006178
    Read this paper
  • Poore EA, Slifka DK, Raué HP, et al. Pre-clinical development of a hydrogen peroxide-inactivated West Nile virus vaccine. Vaccine. 2017,35(2):283-292. doi: 10.1016/j.vaccine.2016.11.080
    Read this paper
  • Zhao H, Fernandez E, Dowd KA, et al. Structural Basis of Zika Virus-Specific Antibody Protection. Cell. 2016,166(4):1016-1027. doi: 10.1016/j.cell.2016.07.020
    Read this paper
  • Vogt MR, Dowd KA, Engle M, et al. Poorly neutralizing cross-reactive antibodies against the fusion loop of West Nile virus envelope protein protect in vivo via Fcgamma receptor and complement-dependent effector mechanisms. J Virol. 2011,85(22):11567-80. doi: 10.1128/JVI.05859-11
    Read this paper
  • Mukherjee S, Lin TY, Dowd KA, et al. The infectivity of prM-containing partially mature West Nile virus does not require the activity of cellular furin-like proteases. J Virol. 2011,85(22):12067-72. doi: 10.1128/JVI.05559-11
    Read this paper
  • Rodenhuis-Zybert IA, Moesker B, da Silva Voorham JM, et al. A fusion-loop antibody enhances the infectious properties of immature flavivirus particles. J Virol. 2011,85(22):11800-8. doi: 10.1128/JVI.05237-11
    Read this paper
  • Dowd KA, Jost CA, Durbin AP, et al. A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virus. PLoS Pathog. 2011,7(6):e1002111. doi: 10.1371/journal.ppat.1002111
    Read this paper
  • Nelson S, Jost CA, Xu Q, et al. Maturation of West Nile virus modulates sensitivity to antibody-mediated neutralization. PLoS Pathog. 2008,4(5):e1000060. doi: 10.1371/journal.ppat.1000060
    Read this paper
  • Oliphant T, Nybakken GE, Engle M, et al. Antibody recognition and neutralization determinants on domains I and II of West Nile Virus envelope protein. J Virol. 2006,80(24):12149-59.
    Read this paper