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Western blot All lanes: INVS antibody IgG at 14ug/ml + K562 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 118, 100, 11 kDa Observed band size: 118 kDa
Western blot All lanes: INVS antibody IgG at 14ug/ml + K562 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 118, 100, 11 kDa Observed band size: 118 kDa
Western blot All lanes: INVS antibody IgG at 14ug/ml + K562 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 118, 100, 11 kDa Observed band size: 118 kDa

INVS Antibody

CSB-PA011769LA01HU
Cusabio
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetINVS
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Overview

  • Supplier
    Cusabio
  • Product Name
    INVS Antibody
  • Delivery Days Customer
    20
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID27130
  • Target name
    INVS
  • Target description
    inversin
  • Target synonyms
    INV, NPH2, NPHP2, inversin, inversion of embryo turning homolog, inversion of embryonic turning, nephrocystin-2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Y283
  • Protein Name
    Inversin
  • Scientific Description
    Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

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Lane 1: A549 Cells; Lane 2: HL60 Cells; Lane 3: Siha Cells; Lane 4: K562 Cells; Probed with Inversin/Nephrocystin 2 Antibody (bs-12437R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
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Figure 1. Western blotting validation for Anti-Inversin INVS Antibody A01628 Western blot analysis of extract of various cells
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