INY-05-040 [2503018-29-7]

TargetMol Chemicals

INY-05-040 [2503018-29-7]

16

Research Use Only

C55H76ClN9O6S

1026.77

INY-05-040 is an AKT degrader that selectively and rapidly degrades all three AKT isoforms, inhibiting downstream signaling and cell proliferation in 288 cancer cell lines, exhibiting anti-cancer activity [1].

C[C@H]1C2=C(N=CN=C2[C@H](O)C1)N3CCN(C([C@H](CNCCCCCCCCCCC(N[C@H](C(=O)N4[C@H](C(N[C@@H](C)C5=CC=C(C=C5)C=6SC=NC6C)=O)C[C@@H](O)C4)C(C)(C)C)=O)C7=CC=C(Cl)C=C7)=O)CC3

-20°C

12352200