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IOX1

HY-12304
MedChem Express
CAS Number5852-78-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.89
Molecular Weight189.17
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Overview

  • Supplier
    MedChem Express
  • Product Name
    IOX1 [5852-78-8]
  • Delivery Days Customer
    10
  • CAS Number
    5852-78-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.89
  • Molecular Formula
    C10H7NO3
  • Molecular Weight
    189.17
  • Scientific Description
    IOX1, 5-Carboxy-8-hydroxyquinoline, is a potent broad-spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 microM, 2.3 microM, 1.8 microM, 0.1 microM and 1.4 microM, respectively[1][2]. IOX1 also inhibits ALKBH5[3].
  • SMILES
    O=C(C1=C2C=CC=NC2=C(O)C=C1)O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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