IOX1

MedChem Express

IOX1 [5852-78-8]

10

5852-78-8

Research Use Only

99.72

C10H7NO3

189.17

IOX1, 5-Carboxy-8-hydroxyquinoline, is a potent broad-spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC 50 values of 0.6 microM, 2.3 microM, 1.8 microM, 0.1 microM and 1.4 microM, respectively [1] [2] . IOX1 also inhibits ALKBH5 [3] .

O=C(C1=C2C=CC=NC2=C(O)C=C1)O

-20°C,2°C to 8°C

12352200