Bio-Connect

IOX4

HY-120110
MedChem Express
CAS Number1154097-71-8
Product group Chemicals
Estimated Purity99.83
Molecular Weight328.33
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Overview

  • Supplier
    MedChem Express
  • Product Name
    IOX4 [1154097-71-8]
  • Delivery Days Customer
    10
  • CAS Number
    1154097-71-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.83
  • Molecular Formula
    C15H16N6O3
  • Molecular Weight
    328.33
  • Scientific Description
    IOX4 is a selective HIF prolyl-hydroxylase 2 ( PHD2 ) inhibitor with an IC 50 value of 1.6 nM, induces HIFalpha in cells and in wildtype mice with marked induction in the brain tissue. IOX4 competes with and displaces 2-oxoglutarate (2OG) at the active site of PHD2 [1] .
  • SMILES
    O=C(C1=CC=C(N2NC=C(N3N=NC=C3)C2=O)N=C1)OC(C)(C)C
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200