Ipatasertib-NH2 [1001382-14-4]

TargetMol Chemicals

Ipatasertib-NH2 [1001382-14-4]

999

1001382-14-4

Chemical

Research Use Only

Ipatasertib-NH2

C21H26ClN5O2

415.92

Ipatasertib-NH2 (GDC-0068-NH2;RG7440-NH2) is a ligand for the target protein AKT used in PROTAC, binding to lenalidomide, a ligand of ubiquitin E3 ligase cereblon (CRBN), via a ten-hydrocarbon linker to form INY-03-041 for AKT degradation[1].

3 years

C[C@H]1C2=C(N=CN=C2[C@H](O)C1)N3CCN(C([C@H](CN)C4=CC=C(Cl)C=C4)=O)CC3

-20°C

12352200