IPN60090 (dihydrochloride)

MedChem Express

IPN60090 (dihydrochloride) [2102101-72-2]

10

2102101-72-2

Research Use Only

99.68

C24H29Cl2F3N8O3

605.44

IPN-60090 dihydrochloride is an orally active and highly selective inhibitor of glutaminase 1 ?( GLS1 ; IC 50 =31 nM ), with no activity observed against GLS-2. IPN-60090 dihydrochloride exhibits excellent physicochemical and pharmacokinetic properties in vivo . IPN-60090 dihydrochloride can be used for solid tumors research, such as lung and ovarian cancers [1] [2] .

O=C(NC)C1=CN(C[C@H](F)CCC2=NN=C(NC(CC3=NC(C)=CC(OC4CC(F)(F)C4)=C3)=O)C=C2)N=N1.[H]Cl.[H]Cl

2°C to 8°C

12352200