
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA137528(IPO4 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200)
IPO4 Antibody
CSB-PA137528
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetIPO4
Overview
- SupplierCusabio
- Product NameIPO4 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID79711
- Target nameIPO4
- Target descriptionimportin 4
- Target synonymsImp4; imp4b; importin-4; importin-4b; ran-binding protein 4; ranBP4
- HostRabbit
- IsotypeIgG
- Protein IDQ8TEX9
- Protein NameImportin-4
- Scientific DescriptionImportin-4 is a protein that in humans is encoded by the IPO4 gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161