Iptacopan

MedChem Express

Iptacopan [1644670-37-0]

9

1644670-37-0

Research Use Only

99.93

C25H30N2O4

422.52

Iptacopan (LNP023) is a first-in-class, orally bioavailable, highly potent and highly selective factor B inhibitor with an IC 50 value of 10 nM. Iptacopan shows direct, reversible, and high-affinity binding to human factor B with a K D of 7.9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G) [1] [2] .

O=C(O)C1=CC=C([C@H]2N(CC3=C(OC)C=C(C)C4=C3C=CN4)CC[C@H](OCC)C2)C=C1

-20°C,2°C to 8°C

12352200