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Iptacopan [1644670-37-0]

Research Use Only
HY-127105
MedChem Express
CAS Number1644670-37-0
Product group Chemicals
Estimated Purity97.97%
Molecular Weight422.52
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Iptacopan [1644670-37-0]
  • Delivery Days Customer
    5
  • CAS Number
    1644670-37-0
  • Certification
    Research Use Only
  • Estimated Purity
    97.97%
  • Molecular Formula
    C25H30N2O4
  • Molecular Weight
    422.52
  • Scientific Description
    Iptacopan (LNP023) is a first-in-class, orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 value of 10 nM. Iptacopan shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G).
  • SMILES
    O=C(O)C1=CC=C([C@H]2N(CC3=C(OC)C=C(C)C4=C3C=CN4)CC[C@H](OCC)C2)C=C1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200