Iptacopan [1644670-37-0]
HY-127105
CAS Number1644670-37-0
Product group Chemicals
Estimated Purity99.95
Molecular Weight422.52
Overview
- SupplierMedChem Express
- Product NameIptacopan [1644670-37-0]
- Delivery Days Customer9
- CAS Number1644670-37-0
- CertificationResearch Use Only
- Estimated Purity99.95
- Hazard Informationh315, h319
- Molecular FormulaC25H30N2O4
- Molecular Weight422.52
- Scientific DescriptionIptacopan (LNP023) is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. Iptacopan exerts a proximal effect in the complement cascade reaction, preventing the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G. Iptacopan can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G)[1][2][3].
- SMILESO=C(O)C1=CC=C([C@H]2N(CC3=C(OC)C=C(C)C4=C3C=CN4)CC[C@H](OCC)C2)C=C1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
MSDS
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![Iptacopan [1644670-37-0]](https://www.targetmol.com/group3/M00/36/03/CgoaEGayNAWEbEMmAAAAAFNqBng319.png)
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