Iptacopan (hydrochloride)

MedChem Express

Iptacopan (hydrochloride) [1646321-63-2]

9

1646321-63-2

Research Use Only

99.88

C25H31ClN2O4

458.98

LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor. LNP023 shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM. LNP023 inhibits factor B with an IC50 value of 10 nM[1][2].

O=C(O)C1=CC=C([C@H]2N(CC3=C(OC)C=C(C)C4=C3C=CN4)CC[C@H](OCC)C2)C=C1.[H]Cl

2°C to 8°C

12352200