IQ-1S [1421610-21-0]

MedChem Express

IQ-1S [1421610-21-0]

5

1421610-21-0

Research Use Only

C15H8N3NaO

269.23

IQ-1S is a prospective inhibitor of NF-kappaB/activating protein 1 (AP-1) activity with an IC50 of 1.8 microM. IQ-1 has binding affinity (Kd values) in the nanomolar range for all three JNKs with Kds of 87 nM, 360 nM, and 390 nM for JNK3, JNK2, and JNK1, respectively.

[Na]O/N=C1C2=C(C3=NC4=CC=CC=C4N=C3\1)C=CC=C2

12352200