IQ-1S (free acid)

MedChem Express

IQ-1S (free acid) [23146-22-7]

10

23146-22-7

99.28

C15H9N3O

247.25

IQ-1S free acid is a prospective inhibitor of NF-kappaB /activating protein 1 ( AP-1 ) activity with an IC 50 of 2.3+/-0.41 microM. IQ-1S free acid has binding affinity (K d values) in the nanomolar range for all three JNK s with K d s of 100 nM, 240 nM, and 360 nM for JNK3 , JNK1 , and JNK2 , respectively.

O/N=C1C2=C(C3=NC4=CC=CC=C4N=C3\1)C=CC=C2

-20°C,2°C to 8°C

12352200