IRAK4-IN-13 [2667681-57-2]

MedChem Express

IRAK4-IN-13 [2667681-57-2]

10

2667681-57-2

Research Use Only

C24H27N9O

457.53

IRAK4-IN-13 (compound 21) is a potent and selective IRAK4 inhibitor with an IC50 of 0.6 nM. IRAK4-IN-13 shows high metabolic clearance with human liver microsomes (HLM) intrinsic clearance is 96 microL/min/mg[1].

CN1CCC(N2N=CC(NC3=NC(OC4(C)CC4)=C5C(C=CC(C6=CN=CN=C6)=N5)=N3)=C2)CC1

12131703