IRAK4-IN-14 [2667681-71-0]
HY-146112
CAS Number2667681-71-0
Product group Chemicals
Estimated Purity99.01
Molecular Weight489.55
Overview
- SupplierMedChem Express
- Product NameIRAK4-IN-14 [2667681-71-0]
- Delivery Days Customer5
- CAS Number2667681-71-0
- CertificationResearch Use Only
- Estimated Purity99.01
- Molecular FormulaC25H28FN9O
- Molecular Weight489.55
- Scientific DescriptionIRAK4-IN-14 (compound 28) is a potent, selective and orally active IRAK4 inhibitor with an IC50 of 0.003 microM. IRAK4-IN-14 shows good PK parameters in rats and mouse. IRAK4-IN-14 shows synergistic in vitro activity against MyD88/CD79 double mutant ABC-DLBCL in combination with Acalabrutinib[1].
- SMILESCC1=NC=C(C2=NC3=C(OC4(C)CC4)N=C(NC5=CN(C6CCN(C)CC6)N=C5)N=C3C=C2F)C=N1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200