IRAK4-IN-15 [2667681-85-6]
HY-146113
CAS Number2667681-85-6
Product group Chemicals
Molecular Weight488.56
Overview
- SupplierMedChem Express
- Product NameIRAK4-IN-15 [2667681-85-6]
- Delivery Days Customer10
- CAS Number2667681-85-6
- CertificationResearch Use Only
- Molecular FormulaC25H29FN10
- Molecular Weight488.56
- Scientific DescriptionIRAK4-IN-15 (compound 35) is a potent and selective IRAK4 inhibitor with an IC50 of 0.002 microM. IRAK4-IN-15 shows good human PK predictions with low intrinsic clearance. IRAK4-IN-15 shows great synergistic in vitro activity against MyD88/CD79 double mutant ABC-DLBCL in combination with Acalabrutinib. [1].
- SMILESCC1=NC=C(C2=NC3=C(NC(C)C)N=C(NC4=CN(C(C5)CC65CN(C)C6)N=C4)N=C3C=C2F)C=N1
- UNSPSC12131703