IRAK4-IN-15 [2667681-85-6]

TargetMol Chemicals

IRAK4-IN-15 [2667681-85-6]

114

Research Use Only

IRAK4-IN-15

C25H29FN10

488.56

IRAK4-IN-15 is a selective and potent IRAK4 inhibitor (IC50: 0.002 microM) with good human PK prediction and low intrinsic clearance.IRAK4-IN-15 in combination with Acalabrutinib exhibited potent synergistic in vitro activity against MyD88/CD79 double mutant ABC-DLBCL.

3 years

CN1CC2(CC(C2)N3C=C(NC4=NC5=C(C(NC(C)C)=N4)N=C(C(F)=C5)C=6C=NC(C)=NC6)C=N3)C1

-20°C

51202000