IRAK4-IN-22 [2170694-05-8]

TargetMol Chemicals

IRAK4-IN-22 [2170694-05-8]

72

Chemical

Research Use Only

IRAK4-IN-22

C28H28FN7O2

513.57

IRAK4-IN-22 is a selective, orally active, potent IRAK4 inhibitor that acts on IRAK4 (IC50: 3 nM) and TAK1 (IC50: 17 nM). IRAK4-IN-21 exhibits potent inhibition of IL-23 production with an IC50 value of 0.10 microM. IRAK4-IN-21 can be used to study autoimmune diseases, such as plaque psoriasis and psoriatic arthritis.

3 years

N([C@@H]1[C@@]2(C[C@]([C@@H]1C(N)=O)(C=C2)[H])[H])C=3C(=CN=C(NC4=CC(C(=O)N5CCCC5)=CC=C4)N3)C=6C=C(F)N=CC6

-20°C

51202000