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Irdabisant [1005402-19-6]

HY-109968
MedChem Express
CAS Number1005402-19-6
Product group Chemicals
Estimated Purity99.38
Molecular Weight313.39
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Irdabisant [1005402-19-6]
  • Delivery Days Customer
    10
  • CAS Number
    1005402-19-6
  • Certification
    Research Use Only
  • Estimated Purity
    99.38
  • Molecular Formula
    C18H23N3O2
  • Molecular Weight
    313.39
  • Scientific Description
    Irdabisant (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant histamine H3 receptor (H3R) inverse agonist/inverse agonist with Ki values of 7.2 nM and 2.0 nM for rat H3R and human H3R, respectively. Irdabisant has relatively low inhibitory activity against hERG current with an IC50 of 13.8 microM. Irdabisant has cognition-enhancing and wake-promoting activities in the rat social recognition model. Irdabisant can be used to research schizophrenia or cognitive impairment[1][2].
  • SMILES
    C[C@H](CCC1)N1CCCOC2=CC=C(C(C=C3)=NNC3=O)C=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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