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Untreated (–) and treated (+) THP-1 whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with IRF3 (phospho Ser386) antibody (GTX130422) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Untreated (–) and treated (+) THP-1 whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with IRF3 (phospho Ser386) antibody (GTX130422) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Untreated (–) and treated (+) THP-1 whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with IRF3 (phospho Ser386) antibody (GTX130422) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

IRF3 (phospho Ser386) antibody

GTX130422
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetIRF3
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Overview

  • Supplier
    GeneTex
  • Product Name
    IRF3 (phospho Ser386) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.04 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3661
  • Target name
    IRF3
  • Target description
    interferon regulatory factor 3
  • Target synonyms
    IIAE7, interferon regulatory factor 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Chiou WC, Lyu YS, Hsia TL, et al. Ergosterol peroxide blocks HDV infection as a novel entry inhibitor by targeting human NTCP receptor. Biomed Pharmacother. 2024,170:116077. doi: 10.1016/j.biopha.2023.116077
    Read this paper
  • Zhang X, Su H, Yu H, et al. A Polysaccharide From Eupolyphaga sinensis Walker With Anti-HBV Activities In Vitro and In Vivo. Front Pharmacol. 2022,13:827128. doi: 10.3389/fphar.2022.827128
    Read this paper
  • Shen JZ, Qiu Z, Wu Q, et al. FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell. 2021,184(2):352-369.e23. doi: 10.1016/j.cell.2020.11.042
    Read this paper
  • Soonthornvacharin S, Rodriguez-Frandsen A, Zhou Y, et al. Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation. Nat Microbiol. 2017,2:17022. doi: 10.1038/nmicrobiol.2017.22
    Read this paper

Datasheet

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