IRF3 (phospho Ser386) antibody
GTX130422
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetIRF3
Overview
- SupplierGeneTex
- Product NameIRF3 (phospho Ser386) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.04 mg/ml
- ConjugateUnconjugated
- Gene ID3661
- Target nameIRF3
- Target descriptioninterferon regulatory factor 3
- Target synonymsIIAE7, interferon regulatory factor 3
- HostRabbit
- IsotypeIgG
- Scientific DescriptionIRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chiou WC, Lyu YS, Hsia TL, et al. Ergosterol peroxide blocks HDV infection as a novel entry inhibitor by targeting human NTCP receptor. Biomed Pharmacother. 2024,170:116077. doi: 10.1016/j.biopha.2023.116077Read this paper
- Zhang X, Su H, Yu H, et al. A Polysaccharide From Eupolyphaga sinensis Walker With Anti-HBV Activities In Vitro and In Vivo. Front Pharmacol. 2022,13:827128. doi: 10.3389/fphar.2022.827128Read this paper
- Shen JZ, Qiu Z, Wu Q, et al. FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell. 2021,184(2):352-369.e23. doi: 10.1016/j.cell.2020.11.042Read this paper
- Soonthornvacharin S, Rodriguez-Frandsen A, Zhou Y, et al. Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation. Nat Microbiol. 2017,2:17022. doi: 10.1038/nmicrobiol.2017.22Read this paper



![WB analysis of wild-type (WT) and IRF3 knockout (KO) HeLa cell extracts using GTX00956 IRF3 antibody [GT1194]. Dilution : 1:1000 Laoding : 25microg](https://www.genetex.com/upload/website/prouct_img/normal/GTX00956/GTX00956_20200327_WB_1_w_23053121_530.webp)

![ICC/IF analysis of COS7 cells transiently transfected with IRF3 plasmid using GTX84288 IRF3 antibody [4D4].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84288/GTX84288_1010_ICCIF_w_23061420_749.webp)
