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Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA011823ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA011823ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA011823ESR1HU at dilution of 1:100

IRF8 Antibody

CSB-PA011823ESR1HU
Cusabio
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetIRF8
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Overview

  • Supplier
    Cusabio
  • Product Name
    IRF8 Antibody
  • Delivery Days Customer
    20
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID3394
  • Target name
    IRF8
  • Target description
    interferon regulatory factor 8
  • Target synonyms
    H-ICSBP; ICSBP; ICSBP1; IMD32A; IMD32B; interferon consensus sequence binding protein 1; interferon regulatory factor 8; IRF-8
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5-TGAnTCA/GAAA-3), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203

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