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ProductsBack/IRF8 Antibody

Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA011823ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA011823ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA011823ESR1HU at dilution of 1:100

IRF8 Antibody

CSB-PA011823ESR1HU

ApplicationsELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetIRF8

Overview

Supplier
Cusabio
Product Name
IRF8 Antibody
Delivery Days Customer
20
Applications
ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID3394
Target name
IRF8
Target description
interferon regulatory factor 8
Target synonyms
H-ICSBP, ICSBP, ICSBP1, IMD32A, IMD32B, IRF-8, interferon regulatory factor 8, interferon consensus sequence binding protein 1
Host
Rabbit
Isotype
IgG
Protein IDQ02556
Protein Name
Interferon regulatory factor 8
Scientific Description
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5-TGAnTCA/GAAA-3), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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