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Irinotecan

M4465
AbMole BioScience
CAS Number97682-44-5
Product group Chemicals
Molecular Weight586.68
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Irinotecan
  • Delivery Days Customer
    9
  • CAS Number
    97682-44-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C33H38N4O6
  • Molecular Weight
    586.68
  • Scientific Description
    Irinotecan is an inhibitor of Topoisomerase I, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex. Irinotecan inhibits the growth of LoVo and HT-29 cells, with IC50s of 15.8 ± 5.1 and 5.17 ± 1.4 uM, respectively.
  • SMILES
    CCC1=C2C=C(OC(=O)N3CCC(CC3)N4CCCCC4)C=CC2=NC5=C1CN6C(=O)C7=C(C=C56)C(O)(CC)C(=O)OC7
  • Storage Instruction
    2-8°C, protect from light, dry, sealed
  • UNSPSC
    12352200

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