IRL 2500 [169545-27-1]

MedChem Express

IRL 2500 [169545-27-1]

10

169545-27-1

Research Use Only

99.0

C36H35N3O4

573.68

IRL 2500 is a potent Endothelin receptor antagonist. IRL 2500 shows IC50?values of 1.3 and 94 nM for ETB?and ETA?receptors, respectively. IRL 2500 inhibits ETB?receptor-mediated blood pressure increase and renal vascular resistance in rats?in vivo[1].

O=C(O)[C@H](CC1=CNC2=CC=CC=C12)NC([C@@H](CC3=CC=C(C4=CC=CC=C4)C=C3)N(C(C5=CC(C)=CC(C)=C5)=O)C)=O

2°C to 8°C

12352200