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IRS1 antibody

Name: IRS1 antibody
SKU: GTX78916_G10
Availability: BackOrder

GTX78916

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetIRS1

Overview

Supplier
GeneTex
Product Name
IRS1 antibody
Delivery Days Customer
9
Application Supplier Note
IHC-P: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID3667
Target name
IRS1
Target description
insulin receptor substrate 1
Target synonyms
HIRS-1, insulin receptor substrate 1
Host
Rabbit
Isotype
IgG
Protein IDP35568
Protein Name
Insulin receptor substrate 1
Scientific Description
This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Lo WC, Chiou CS, Tsai FC, et al. Platelet-Derived Biomaterials Inhibit Nicotine-Induced Intervertebral Disc Degeneration Through Regulating IGF-1/AKT/IRS-1 Signaling Axis. Cell Transplant. 2021,30:9636897211045319. doi: 10.1177/09636897211045319
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Lo WC, Dubey NK, Tsai FC, et al. Amelioration of Nicotine-Induced Osteoarthritis by Platelet-Derived Biomaterials Through Modulating IGF-1/AKT/IRS-1 Signaling Axis. Cell Transplant. 2020,29:963689720947348. doi: 10.1177/0963689720947348
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Lin IC, Wu CW, Tain YL, et al. High fructose diet induces early mortality via autophagy factors accumulation in the rostral ventrolateral medulla as ameliorated by pioglitazone. J Nutr Biochem. 2019,69:87-97. doi: 10.1016/j.jnutbio.2019.03.014
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Wu CW, Hung CY, Hirase H, et al. Pioglitazone reversed the fructose-programmed astrocytic glycolysis and oxidative phosphorylation of female rat offspring. Am J Physiol Endocrinol Metab. 2019,316(4):E622-E634. doi: 10.1152/ajpendo.00408.2018
Read this paper