Islatravir

MedChem Express

Islatravir [865363-93-5]

10

865363-93-5

Research Use Only

99.94

C12H12FN5O3

293.25

Islatravir (MK-8591) is a potent anti- HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC 50 s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. Islatravir is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

NC1=NC(F)=NC2=C1N=CN2[C@@H]3O[C@](CO)(C#C)[C@H](O)C3

-20°C,2°C to 8°C

12352200