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Chemical Structure
iso-Leucettinib-21
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AG-MR-C0048
Product group Chemicals
Overview
- SupplierAdipoGen Life Sciences
- Product Nameiso-Leucettinib-21
- Delivery Days Customer10
- CertificationResearch Use Only
- Scientific DescriptionChemical. CAS: 3032977-73-1. Formula: C18H22N4O2S. MW: 358.5. Soluble in DMSO (10mM) or ethanol. Kinase inactive isomer of Leucettinib-21 (IC50 DYRK1A > 10 microM). Should be used as a negative control for Leucettinb-21 (Prod. No. AG-MR-C0047). Does not inhibit the phosphorylation of Tau at Thr212 and cyclin D1 at Thr286, native DYRK1A in HT-22 cells and does not trigger cell apoptotic cell death. Does not correct cognitive deficits in Ts65Dn model of Down syndrome and other models. - Kinase inactive isomer of Leucettinib-21 (IC50 DYRK1A > 10 microM). Should be used as a negative control for Leucettinb-21 (Prod. No. AG-MR-C0047). Does not inhibit the phosphorylation of Tau at Thr212 and cyclin D1 at Thr286, native DYRK1A in HT-22 cells and does not trigger cell apoptotic cell death. Does not correct cognitive deficits in Ts65Dn model of Down syndrome and other models.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200