Chemical Structure
Chemical Structure
iso-Leucettinib-21 [3032977-73-1] [3032977-73-1]
AG-MR-C0048
CAS Number3032977_73_1
Product group Chemicals
Estimated Purity>99%
Molecular Weight358.5
Overview
- SupplierAdipoGen Life Sciences
- Product Nameiso-Leucettinib-21 [3032977-73-1] [3032977-73-1]
- Delivery Days Customer10
- CAS Number3032977_73_1
- CertificationResearch Use Only
- Estimated Purity>99%
- Hazard InformationWarning
- Molecular FormulaC18H22N4O2S
- Molecular Weight358.5
- Scientific DescriptionChemical. CAS: 3032977-73-1. Formula: C18H22N4O2S. MW: 358.5. Soluble in DMSO (10mM) or ethanol. Kinase inactive isomer of Leucettinib-21 (IC50 DYRK1A > 10 microM). Should be used as a negative control for Leucettinb-21 (Prod. No. AG-MR-C0047). Does not inhibit the phosphorylation of Tau at Thr212 and cyclin D1 at Thr286, native DYRK1A in HT-22 cells and does not trigger cell apoptotic cell death. Does not correct cognitive deficits in Ts65Dn model of Down syndrome and other models. - Kinase inactive isomer of Leucettinib-21 (IC50 DYRK1A > 10 microM). Should be used as a negative control for Leucettinb-21 (Prod. No. AG-MR-C0047). Does not inhibit the phosphorylation of Tau at Thr212 and cyclin D1 at Thr286, native DYRK1A in HT-22 cells and does not trigger cell apoptotic cell death. Does not correct cognitive deficits in Ts65Dn model of Down syndrome and other models.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12161509