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ProductsBack/iso-WAY-260022 [1214914-38-1]

iso-WAY-260022 [1214914-38-1]

HY-10427A
MedChem Express
CAS Number1214914-38-1
Product group Chemicals
Molecular Weight400.48
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Overview

  • Supplier
    MedChem Express
  • Product Name
    iso-WAY-260022 [1214914-38-1]
  • Delivery Days Customer
    5
  • CAS Number
    1214914-38-1
  • Certification
    Research Use Only
  • Molecular Formula
    C21H31F3N2O2
  • Molecular Weight
    400.48
  • Scientific Description
    iso-WAY-260022 (Compound 13R) is an orally active, brain-penetrant and selective norepinephrine transporter (hNET) inhibitor with an IC50 value of 140 nM. iso-WAY-260022 also shows inhibitory effects on human serotonin (hSERT) and dopamine transporters (hDAT). iso-WAY-260022 inhibits norepinephrine reuptake and increases hypothalamic norepinephrine levels to regulate thermoregulatory center function. iso-WAY-260022 is promising for research of vasomotor symptoms, such as menopausal hot flushes, night sweats[1].
  • SMILES
    C[C@H](N[C@@H](C1)C)CN1C[C@@H](C2=CC(OC(F)(F)F)=CC=C2)C3(CCCCC3)O
  • UNSPSC
    12352200

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