Isomaltulose monohydrate [58024-13-8]

TargetMol Chemicals

Isomaltulose monohydrate [58024-13-8]

16

58024-13-8

Research Use Only

C12H24O12

360.31

Isomaltulose monohydrate is an fMLP inhibitor that also inhibits Src kinase, ERK1/2, p38, and AKT phosphorylation signals in immune regulation. It interferes with the interaction between the betagamma subunit of the fMLP receptor Gi protein and downstream molecules, thereby inhibiting fMLP-induced respiratory burst. Isomaltulose monohydrate inhibits fMLP (0.1 microM)-induced superoxide anion production (IC50: 1.98 microM), cathepsin G release (IC50: 2.76 microM), and chemotaxis. It can improve excessive activation of neutrophils and reduce inflammation or tissue damage. Derivatives of Isomaltulose monohydrate have been found to inhibit FSGS-related TRPC6 functional mutants [1].

O(C[C@H]([C@H]([C@@H](C(CO)=O)O)O)O)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O.O

-20°C

12352200