Isonanangenine B [1623153-14-9]

TargetMol Chemicals

Isonanangenine B [1623153-14-9]

72

1623153-14-9

Chemical

Research Use Only

Isonanangenine B

C21H32O6

380.48

Isonanangenine B is a drimane sesquiterpene lactone that has been found in Aspergillus. It decreases survivin mRNA expression in a reporter assay when used at concentrations of 13.6, 18.42, and 26.31 microM. Isonanagenine B (18.42 microM) inhibits STAT3 and NF-kappaB binding to the survivin promoter in chromatin immunoprecipitation (ChIP) assays. It also induces apoptosis in COLO 320DM cells.

3 years

[H][C@@]12[C@H](OC(=O)CCCCC)C=C3C(=O)OC[C@]3(O)[C@@]1(C)[C@H](O)CCC2(C)C

-20°C

12352200