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Isoscopoletin [776-86-3]

HY-N1365
MedChem Express
CAS Number776-86-3
Product group Chemicals
Estimated Purity99.92
Molecular Weight192.17
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Isoscopoletin [776-86-3]
  • Delivery Days Customer
    10
  • CAS Number
    776-86-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.92
  • Molecular Formula
    C10H8O4
  • Molecular Weight
    192.17
  • Scientific Description
    Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active constituent in Artemisia argyi leaves. Isoscopoletin shows substantial inhibition against cell proliferation, with IC50s of 4.0 microM and 1.6 microM for human CCRF-CEM leukaemia cells and multidrug resistant subline CEM/ADR5000, respectively[1]. Isoscopoletin (6-Hydroxy-7-methoxycoumarin) possesses inhibitory activity against HBV replication[2]. Isoscopoletin exhibits anti-inflammatory activity through inhibition of MAPK/NF-kappaB/STAT/AKT signaling pathway[3].
  • SMILES
    O=C1C=CC2=CC(O)=C(OC)C=C2O1
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

MSDS

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