Isosilybin A

MedChem Express

Isosilybin A [142796-21-2]

10

142796-21-2

Research Use Only

99.63

C25H22O10

482.44

Isosilybin A, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt-NF-kappaB-androgen receptor (AR) axis[1][2].

O=C1[C@H](O)[C@@H](C2=CC=C(O[C@H](C3=CC=C(O)C(OC)=C3)[C@@H](CO)O4)C4=C2)OC5=CC(O)=CC(O)=C15

-20°C,2°C to 8°C

12352200