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ISRIB (trans-isomer)

HY-12495
MedChem Express
CAS Number1597403-47-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.49
Molecular Weight451.34
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ISRIB (trans-isomer) [1597403-47-8]
  • Delivery Days Customer
    10
  • CAS Number
    1597403-47-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.49
  • Molecular Formula
    C22H24Cl2N2O4
  • Molecular Weight
    451.34
  • Scientific Description
    ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC 50 of 5 nM. ISRIB potently reverses the effects of eIF2alpha phosphorylation (IC 50 =5 nM).
  • SMILES
    O=C(N[C@H]1CC[C@H](NC(COC2=CC=C(Cl)C=C2)=O)CC1)COC3=CC=C(Cl)C=C3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200