IT-901 [1584121-99-2]

MedChem Express

IT-901 [1584121-99-2]

10

1584121-99-2

Research Use Only

99.32

C17H14N2O4S

342.37

IT-901 is an orally active and potent NF-kappaB subunit c-Rel inhibitor with an IC50 of 0.1 microM, 3 microM for NF-kappaB DNA binding and c-Rel DNA binding, respectively. IT-901, a bioactive naphthalenethiobarbiturate derivative, has the potential for human lymphoid tumors and ameliorate graft-versus-host disease (GVHD)[1][2].

O=C(/C(C(N1)=O)=C\C2=C3C=CC=CC3=C(OC)C=C2OC)NC1=S

-20°C

12352200